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Technical Specification: Plant Biology Assay Kits

Official Source Verification

This documentation is published by Beijing Solarbio Science & Technology Co., Ltd. For product procurement and commercial inquiries, visit the Solarbio Store.

1. Product Range

Assay SKU Detection Method Wavelength Detection Limit Linear Range Sample Types
Chlorophyll Content Assay BC0990 Ethanol extraction + spectrophotometry 665/649 nm 0.5 mg/L 1–50 mg/L chl a+b Leaf, algae, chloroplast
Carotenoid Assay BC0995 Spectrophotometric (ethanol extract) 470 nm 0.2 mg/L 0.5–20 mg/L Leaf, fruit, flower
Proline Content Assay BC0290 Ninhydrin colorimetric 520 nm 1 μg/g FW 2–50 μg/g FW Leaf, root, seed
MDA (Plant) Assay Kit BC0020-Plant TBA reaction (plant-optimized) 532/600 nm 0.5 nmol/mL 1–50 nmol/mL Leaf, root, fruit
Nitrate Reductase Assay BC0080 Sulfanilamide-NED (nitrite detection) 540 nm 0.1 μmol NO₂⁻/h/g FW 0.5–20 μmol NO₂⁻/h/g FW Leaf, root
H₂O₂ Assay (Plant) BC0060-Plant Titanium sulfate 415 nm 1 μmol/g FW 2–100 μmol/g FW Leaf, root
Soluble Sugar Assay BC5450 Anthrone-sulfuric acid 620 nm 10 μg/g FW 20–500 μg/g FW Leaf, root, fruit
Starch Content Assay BC0700 Anthrone (amylase digestion) 620 nm 50 μg/g FW 100–2000 μg/g FW Leaf, seed, tuber
Total Phenolic Assay BC1065 Folin-Ciocalteu (GAE equiv) 760 nm 5 μg GAE/g 10–200 μg GAE/g Leaf, fruit, bark
Flavonoid Assay BC1070 AlCl₃ colorimetric (rutin equiv) 510 nm 10 μg RE/g 20–500 μg RE/g Leaf, flower, herb
Abscisic Acid (ABA) Assay BC1188 ELISA (competitive) 450 nm 1 ng/mL 2–100 ng/mL Leaf, xylem sap
Indole-3-Acetic Acid (IAA) Assay BC1193 ELISA (competitive) 450 nm 0.5 ng/mL 1–50 ng/mL Leaf, root, stem
Gibberellic Acid (GA₃) Assay BC1197 ELISA (competitive) 450 nm 1 ng/mL 2–50 ng/mL Leaf, seed

2. Detailed Assay Principles

2.1 Chlorophyll — Spectrophotometric Method (BC0990)

Chlorophylls a and b are extracted in 95% ethanol and quantified spectrophotometrically using the specific absorption coefficients in ethanol.

Chl a (in 95% ethanol): λ_max = 665 nm (ε = 83.9 L·g⁻¹·cm⁻¹)
Chl b (in 95% ethanol): λ_max = 649 nm (ε = 48.5 L·g⁻¹·cm⁻¹)
Carotenoids: λ = 470 nm (combined signal)

Calculations (Lichtenthaler 1987, ethanol-based):

Chl a (mg/L) = 13.95 × A₆₆₅ − 6.88 × A₆₄₉
Chl b (mg/L) = 24.96 × A₆₄₉ − 7.32 × A₆₆₅
Chl a + b (mg/L) = 6.63 × A₆₆₅ + 18.08 × A₆₄₉
Carotenoids (mg/L) = (1000 × A₄₇₀ − 2.05 × Chl a − 114.8 × Chl b) / 245
Parameter Specification
Assay type Endpoint spectrophotometric
Wavelengths 665, 649, 470 nm
Limit of detection 0.5 mg/L (each pigment)
Linear range 1–50 mg/L
Intra-assay CV <5% (n=20, 10 mg/L)
Inter-assay CV <8% (n=6 lots)
Extraction solvent 95% ethanol (v/v)
Extraction time 24 h at 4°C (dark)
Minimum sample 0.05 g fresh leaf
Solvent volume 1 mL / 0.1 g tissue

Protocol:

Step Detail
1 Weigh 0.1 g fresh leaf (avoid major veins)
2 Add 1 mL 95% ethanol, grind in mortar or bead mill
3 Transfer to tube, incubate in dark at 4°C for 24 h (or 60°C for 30 min for rapid extraction)
4 Centrifuge at 5000×g, 5 min
5 Read supernatant at 665, 649, 470 nm against ethanol blank
6 Calculate using equations above

Reference Values:

Plant Species Chl a (mg/g FW) Chl b (mg/g FW) Chl a/b ratio
Arabidopsis (rosette) 0.8–1.5 0.3–0.6 2.5–3.5
Rice (flag leaf) 2.0–4.0 0.6–1.2 3.0–3.5
Maize (leaf) 1.5–3.0 0.5–0.9 2.8–3.2
Spinach (mature leaf) 1.0–2.0 0.4–0.8 2.2–3.0
Wheat (flag leaf) 2.0–3.5 0.5–1.0 3.0–4.0
Soybean (trifoliate) 1.5–3.0 0.5–0.8 2.8–3.5

Stress-Induced Changes: - Drought: Chl ↓ 20–50%, Chl a/b ratio increases - Salt stress: Chl ↓ 30–60%, Chl a/b ratio may increase or decrease - Nitrogen deficiency: Chl ↓ primarily, Chl a/b ratio increases - Light stress: Chl a/b ratio decreases (increased antenna size)

Critical Note: Chlorophyll is photolabile. Perform all extraction steps in dim light or wrap tubes in aluminum foil. Do not use methanol or acetone without recalibrating equations (different absorption coefficients).

2.2 Carotenoid Assay (BC0995)

Carotenoids, including β-carotene and xanthophylls, are extracted together with chlorophyll and measured at 470 nm.

Parameter Specification
Wavelength 470 nm
Limit of detection 0.2 mg/L
Linear range 0.5–20 mg/L
Reference range (leaf) 0.2–0.8 mg/g FW

Calculation (correcting for chlorophyll overlap at 470 nm):

Carotenoids (mg/L) = (1000 × A₄₇₀ − 2.05 × Chl a − 114.8 × Chl b) / 245

2.3 Proline — Ninhydrin Colorimetric Method (BC0290)

Proline accumulates in plants under osmotic stress (drought, salinity, cold) as a compatible osmolyte. The assay uses the specific reaction of proline with ninhydrin in acidic conditions to form a red chromophore.

Proline + Ninhydrin ──[Glacial acetic acid, 100°C, 30 min]──→
    Proline-ninhydrin complex (red, λ_max = 520 nm)
Parameter Specification
Assay type Endpoint colorimetric
Wavelength 520 nm
Limit of detection 1 μg/g FW
Linear range 2–50 μg/g FW
Intra-assay CV <6%
Reaction temperature 100°C (boiling water bath)
Reaction time 30 min
Extraction 3% sulfosalicylic acid (1 mL per 0.1 g tissue)
Solvent for extraction Toluene (separates proline-ninhydrin complex)

Protocol:

Step Detail
1 Homogenize 0.1 g tissue in 1 mL 3% sulfosalicylic acid
2 Centrifuge at 5000×g, 10 min
3 Collect 200 μL supernatant, add 200 μL ninhydrin reagent + 200 μL glacial acetic acid
4 Boil at 100°C for 30 min (sealed tube)
5 Cool on ice, add 1 mL toluene, vortex 15 s
6 Allow phase separation (15 min), read upper toluene phase at 520 nm

Reference Values:

Species Control (μg/g FW) Stress (μg/g FW) Stress Condition
Arabidopsis 5–15 30–80 200 mM NaCl, 48 h
Rice 10–30 50–200 Drought (15% PEG), 5 d
Wheat 10–25 40–150 150 mM NaCl, 24 h
Maize 5–20 30–120 Drought, 7 d

2.4 MDA (Plant) — TBA Method (BC0020-Plant)

The plant-optimized MDA kit accounts for plant-specific interferences (phenolics, sugars) that are less abundant in animal tissues.

MDA + 2 × Thiobarbituric Acid ──[95°C, pH 3.5, 40 min]──→
    MDA-TBA₂ adduct (red, 532 nm; 600 nm correction)
Parameter Specification
Wavelength 532 nm (600 nm correction)
Detection limit 0.5 nmol/mL
Linear range 1–50 nmol/mL
Intra-assay CV <7%
Extraction buffer 10% TCA (trichloroacetic acid)
Sample amount 0.1 g tissue in 1 mL TCA

Reference Values:

Plant Control (nmol/g FW) Stress (nmol/g FW)
Rice leaf 5–15 15–50 (salt stress)
Arabidopsis 3–10 10–30 (drought)
Maize leaf 5–20 20–60 (chilling)

2.5 Nitrate Reductase (NR) Assay (BC0080)

Nitrate reductase catalyzes the first and rate-limiting step of nitrate assimilation, reducing NO₃⁻ to NO₂⁻.

NO₃⁻ + NADH ──[NR, 30°C, dark, 30 min]──→ NO₂⁻ + NAD⁺ + H₂O
NO₂⁻ + Sulfanilamide + NED ──[Acidic]──→ Azo dye (pink, 540 nm)
Parameter Specification
Assay type In vitro activity
Wavelength 540 nm
Detection limit 0.1 μmol NO₂⁻/h/g FW
Linear range 0.5–20 μmol NO₂⁻/h/g FW
Intra-assay CV <8%
Incubation 30°C, 30 min, dark
Substrates KNO₃ (50 mM) + NADH (0.2 mM)

Critical Note: NR is highly labile. Harvest tissue in mid-morning (light phase), process immediately at 4°C, and complete the assay within 2 h. The assay must be performed in the dark (light inactivates NR).

Reference Values:

Species NR Activity (μmol NO₂⁻/h/g FW)
Maize leaf (light) 5–15
Rice leaf 3–10
Arabidopsis 2–8
Spinach 4–12

2.6 H₂O₂ Assay (BC0060-Plant)

H₂O₂ + Ti⁴⁺ + 2 H₂O → H₂TiO₄ (yellow peroxotitanate complex, 415 nm)
Parameter Specification
Wavelength 415 nm
Detection limit 1 μmol/g FW
Linear range 2–100 μmol/g FW
Extraction Cold acetone or TCA
Reaction time 10 min at RT

Reference Values: Leaf H₂O₂ is typically 5–20 μmol/g FW under normal conditions and can increase to 30–100 μmol/g FW under stress.

2.7 Soluble Sugar — Anthrone Method (BC5450)

Carbohydrate (furfurol derivative from conc. H₂SO₄) + Anthrone → Blue-green complex (620 nm)
Parameter Specification
Wavelength 620 nm
Detection limit 10 μg/g FW
Linear range 20–500 μg/g FW (glucose equivalents)
Extraction 80% ethanol, 80°C, 30 min
Standard Glucose (provided in kit)

Reference Values:

Species Control (% DW) Stress
Arabidopsis leaf 1–3% Up to 8% (drought)
Rice leaf 3–8% 5–15% (salt)
Maize leaf 2–5% 4–10% (cold)

2.8 Starch Content (BC0700)

Starch is first digested to glucose by amylase/amyloglucosidase, then glucose is measured by the anthrone method.

Starch ──[Amylase, 60°C, 30 min]──→ Dextrins
Dextrins ──[Amyloglucosidase, 60°C, 30 min]──→ Glucose
Glucose ──[Anthrone/H₂SO₄]──→ Blue-green (620 nm)
Parameter Specification
Detection limit 50 μg/g FW
Linear range 100–2000 μg/g FW (glucose equiv)

2.9 Total Phenolics — Folin-Ciocalteu (BC1065)

Phenolic OH + Folin-Ciocalteu reagent (Mo⁶⁺/W⁶⁺)
    ──[Na₂CO₃, alkalin]──→ Reduced Mo⁵⁺/W⁵⁺ (blue, 760 nm)
Parameter Specification
Wavelength 760 nm
Detection limit 5 μg GAE/g
Linear range 10–200 μg GAE/g
Standard Gallic acid (GAE)
Reaction time 30 min at RT (dark)

Reference Values:

Plant Material Total Phenolics (mg GAE/g DW)
Green tea leaves 50–150
Grape (skin) 20–50
Blueberry 15–40
Spinach leaf 5–15
Arabidopsis leaf 3–10

2.10 Flavonoid Assay (BC1070)

Flavonoid + AlCl₃ ──[Ethanol, RT]──→ Flavonoid-Al³⁺ complex (yellow, 510 nm)
Parameter Specification
Wavelength 510 nm
Detection limit 10 μg RE/g
Linear range 20–500 μg RE/g
Standard Rutin (RE)
Reaction time 10 min at RT

2.11 Plant Hormone ELISAs (ABA, IAA, GA₃)

These competitive ELISA kits use a HRP-conjugated hormone tracer and TMB substrate.

Parameter ABA (BC1188) IAA (BC1193) GA₃ (BC1197)
Assay type Competitive ELISA Competitive ELISA Competitive ELISA
Detection limit 1 ng/mL 0.5 ng/mL 1 ng/mL
Linear range 2–100 ng/mL 1–50 ng/mL 2–50 ng/mL
Intra-assay CV <8% <9% <9%
Inter-assay CV <15% <15% <15%
Recovery (spiked tissue extract) 85–115% 80–120% 85–115%
Cross-reactivity ABA >95% IAA >95% GA₃ >90%
Sample type Leaf (0.5 g), xylem sap (100 μL) Leaf (0.5 g), root (0.5 g) Leaf (0.3 g), seed (0.1 g)
Extraction 80% MeOH + BHT 80% MeOH 80% MeOH
Incubation time 2 h + 15 min TMB 2 h + 15 min TMB 2 h + 15 min TMB

Sample Extraction for Hormones: Plant tissue (0.3–0.5 g) is extracted in 80% methanol containing 10 mg/L BHT (butylated hydroxytoluene) at 4°C for 12–16 h. The extract is centrifuged, dried under N₂, and reconstituted in assay buffer. Further purification by C18 SPE cartridge is recommended for tissues with high pigment or phenolic content.

3. Sample Preparation Guide

Assay Recommended Tissue Amount Extraction Solvent Special Notes
Chlorophyll 0.1 g leaf 95% ethanol, 24 h, 4°C, dark Avoid major veins; process in dim light
Carotenoids 0.1 g leaf Same as chlorophyll (read at 470 nm) Co-extracted with chlorophyll
Proline 0.1 g leaf/root 3% sulfosalicylic acid Use fresh tissue; avoid drying
MDA 0.1 g leaf 10% TCA (plant-optimized) Do not use PBS or sucrose-containing buffers
NR 0.2 g leaf In situ in assay buffer (no extraction) Must perform in dark; process within 2 h
H₂O₂ 0.1 g leaf Cold acetone or 5% TCA Extract quickly; H₂O₂ degrades rapidly
Soluble Sugar 0.1 g leaf (DW) 80% ethanol, 80°C Use oven-dried (80°C, 48 h) or fresh tissue
Starch Residue from sugar extraction DMSO + heat Use pellet from sugar extraction
Total Phenolics 0.1 g DW 70% methanol, sonicate Protect from light; use dark glass vials
ABA 0.5 g leaf 80% MeOH, 4°C, 12 h C18 SPE recommended for clean-up

4. Troubleshooting Guide

Problem Likely Cause Solution
Chlorophyll A₆₆₅ exceeds 2.0 Tissue sample too large Reduce sample to 0.05 g; dilute extract 1:2
Proline blank is colored Ninhydrin reagent degraded or overheated Prepare fresh ninhydrin; reduce heating time
MDA absorbance decrease after extraction TBA chromophore instability Read within 30 min after extraction
NR activity zero Tissue harvested in dark phase Harvest 2–4 h into light cycle
H₂O₂ blank high Titanium reagent hydrolyzed Prepare fresh H₂SO₄/Ti solution weekly
Anthrone blank is green Sulfuric acid concentration incorrect Ensure H₂SO₄ is >95% and cooled before use
Hormone binding below B₀ Extract contains organic solvents Evaporate MeOH completely and reconstitute in buffer

5. Stress Marker Panel Recommendations

Stress Type Primary Markers Secondary Markers Expected Change
Drought Proline (⬆), MDA (⬆), Soluble Sugars (⬆) Chlorophyll (⬇), NR (⬇), ABA (⬆) Proline 3–10×; MDA 2–3×; Sugars 1.5–3×
Salinity Proline (⬆), MDA (⬆), H₂O₂ (⬆) Chlorophyll (⬇), Carotenoids (variable) Proline 5–20×; H₂O₂ 2–5×
Cold Proline (⬆), Soluble Sugars (⬆), MDA (⬆) Chlorophyll (⬇), Phenolics (⬆) Sugars 2–4×; Proline 2–5×
Heat MDA (⬆), H₂O₂ (⬆), Proline (⬆) Chlorophyll (⬇), NR (⬇) MDA 2–4×; H₂O₂ 2–3×
Heavy metal (Cd) MDA (⬆), H₂O₂ (⬆), GSH (⬆) Chlorophyll (⬇), Proline (⬆) MDA 2–5×; GSH 1.5–3×
UV-B Phenolics (⬆), Flavonoids (⬆), MDA (⬆) Chlorophyll (⬇), Carotenoids (⬆) Phenolics 2–5×; UV-absorbing compounds
Pathogen defense Phenolics (⬆), H₂O₂ (⬆), ABA (⬆) Flavonoids (⬆), Salicylic acid H₂O₂ burst 2–10×; phenolics 2–3×

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